Testing Data
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using eIF4B (Ab-422) Antibody (E021513).)
anti-Human, Mouse eIF4B Antibody | anti-eIF4B antibody
eIF4B (Ab-422) Antibody
Gene Names
EIF4B; EIF-4B; PRO1843
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Synonyms
eIF4B; eIF4B (Ab-422) Antibody; anti-eIF4B antibody
Reactivity
Human, Mouse
Specificity
eIF4B (Ab-422) Antibody detects endogenous levels of total eIF4B protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
572
Applicable Applications for anti-eIF4B antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:100
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from Human eIF4B around the phosphorylation site of Serine 422 (T-G-SP-E-S).
Preparation and Storage
Store at-20 degree C for 1 year
Testing Data
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using eIF4B (Ab-422) Antibody (E021513).)
Testing Data
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using eIF4B (Ab-422) Antibody (E021513).)
Product Categories/Family for anti-eIF4B antibody
References
Gingras, A.C. et al. (2001) Genes Dev. 15, 807-826. Duncan, R. and Hershey, J.W. (1985) J. Biol. Chem. 260, 5493-5497. Duncan, R.F. and Hershey, J.W. (1989) J. Cell Biol. 109, 1467-1481.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
64,805 Da
NCBI Official Full Name
eukaryotic translation initiation factor 4B isoform 3
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 4B
NCBI Official Symbol
EIF4B
NCBI Official Synonym Symbols
EIF-4B; PRO1843
NCBI Protein Information
eukaryotic translation initiation factor 4B
UniProt Protein Name
Eukaryotic translation initiation factor 4B
Protein Family
UniProt Gene Name
EIF4B
UniProt Synonym Gene Names
eIF-4B
Uniprot Description
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Research Articles on eIF4B
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Product Notes
The eIF4B eif4b (Catalog #AAA857600) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The eIF4B (Ab-422) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's eIF4B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:100. Researchers should empirically determine the suitability of the eIF4B eif4b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "eIF4B, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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