Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using CD88/C5aR (Ab-338) antibody.)
anti-Human, Mouse CD88/C5aR Antibody | anti-CD88/C5aR antibody
CD88/C5aR (Ab-338) Antibody
Gene Names
C5AR1; C5A; C5AR; C5R1; CD88
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CD88/C5aR; CD88/C5aR (Ab-338) Antibody; C5AR; C5AR1; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; CD88 antigen; anti-CD88/C5aR antibody
Reactivity
Human, Mouse
Specificity
CD88/C5aR (Ab-338) antibody detects endogenous levels of total CD88/C5aR protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
350
Applicable Applications for anti-CD88/C5aR antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human CD88/C5aR around the phosphorylation site of serine 338(T-R-SP-T-V).
Preparation and Storage
Store at-20 degree C for 1 year.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using CD88/C5aR (Ab-338) antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using CD88/C5aR (Ab-338) antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, treated with PMA (125ng/ml, 30mins), using CD88/C5aR (Ab-338) antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, treated with PMA (125ng/ml, 30mins), using CD88/C5aR (Ab-338) antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells, using CD88/C5aR (Ab-338) antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells, using CD88/C5aR (Ab-338) antibody.)
Product Categories/Family for anti-CD88/C5aR antibody
References
W Fureder, J. Immunol., Sep 1995; 155: 3152. T Werfel, J. Immunol., Aug 1996; 157: 1729. Anthony A. Floreani, J. Immunol., May 1998; 160: 5073. M Burg, J. Immunol., Dec 1996; 157: 5574.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
C5a anaphylatoxin chemotactic receptor 1
NCBI Official Synonym Full Names
complement C5a receptor 1
NCBI Official Symbol
C5AR1
NCBI Official Synonym Symbols
C5A; C5AR; C5R1; CD88
NCBI Protein Information
C5a anaphylatoxin chemotactic receptor 1
UniProt Protein Name
C5a anaphylatoxin chemotactic receptor 1
UniProt Gene Name
C5AR1
UniProt Synonym Gene Names
C5AR; C5R1; C5a-R; C5aR
Uniprot Description
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Research Articles on CD88/C5aR
Similar Products
Product Notes
The CD88/C5aR c5ar1 (Catalog #AAA859654) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CD88/C5aR (Ab-338) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD88/C5aR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000. Researchers should empirically determine the suitability of the CD88/C5aR c5ar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD88/C5aR, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
