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Testing Data

Hsp90 beta Active Protein | HSP90AB1 active protein

Recombinant Human HSP90 beta, native sequence

Gene Names
HSP90AB1; HSP84; HSPC2; HSPCB; D6S182; HSP90B
Reactivity
Human
Applications
Western Blot, ELISA, Immunoprecipitation
Synonyms
Hsp90 beta; Recombinant Human HSP90 beta; native sequence; FLJ26984; Hsp84; Hsp90; Hsp90B; HspC2; HspCB; HSP90AB1 active protein
Ordering
For Research Use Only!
Host
Human
Reactivity
Human
Form/Format
Multi-step Chromatographically Purified
Concentration
2.4mg/mL (varies by lot)
Sequence Length
724
Applicable Applications for HSP90AB1 active protein
Western Blot (WB) control, Chaperone assays, Inhibitor/binding assays, ELISA (EIA) reference standard, Co-IP
Certificate of Analysis
This product has been certified >90% pure using SDS-PAGE analysis.
Conjugate Tag
No tags
Expression System
Baculovirus/Hi5 insect cells
Storage Buffer
20mM Tris, pH 7.5, 175 mM NaCl, 0.1 mM EDTA, 10% glycerol, 1 mM DTT
Preparation and Storage
4 degree C

Testing Data

Testing Data
Related Product Information for HSP90AB1 active protein
Background Info: Molecular weight of approximately 90kDa
Native sequence

Scientific Background: Hsp90 is a highly conserved and essential stress protein Hsp90 is a highly conserved and essential stress protein
Product Categories/Family for HSP90AB1 active protein
References
1. Arlander SJH, et al. (2003) J Biol Chem 278: 52572-52577. 2. Pearl H, et al. (2001) Adv Protein Chem 59:157-186. 3. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 4. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 5. Pratt W, Toft D. (1997) Endocr Rev 18: 306-360. 6. Pratt WB. (1998) Proc Soc Exptl Biol Med 217: 420-434. 7. Whitesell L, et al. (1994) Proc Natl Acad Sci USA 91: 8324- 8328.
1. Prinsloo, E., Kramer, A.H., Edkins, A.L. and Blatch, G.L. (2012). STAT3 interacts directly with Hsp90. IUBMB Life. 64 (3), 266-273. doi: 10.1002/iub.607

2. Tsou, Y. et al. (2013). Heat Shock protein 90: Role in Enterovirus 71 Entry and Assembly and Potential Target for Therapy. PLoS ONE. 8(10): e77133. doi:10.1371/journal.pone.0077133
3. Hunter, M. C. et al. (2014). Hsp90 Binds Directly to Fibronectin (FN) and Inhibition Reduces the Extracellular Fibronectin Matrix in Breast Cancer Cells. PLoS One. 9(1):e86842. doi: 10.1371/journal.pone.0086842.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
90kD
NCBI Official Full Name
heat shock protein HSP 90-beta isoform a
NCBI Official Synonym Full Names
heat shock protein 90kDa alpha (cytosolic), class B member 1
NCBI Official Symbol
HSP90AB1
NCBI Official Synonym Symbols
HSP84; HSPC2; HSPCB; D6S182; HSP90B
NCBI Protein Information
heat shock protein HSP 90-beta; HSP90-beta; heat shock 84 kDa; heat shock 90kD protein 1, beta
UniProt Protein Name
Heat shock protein HSP 90-beta
Protein Family
UniProt Gene Name
HSP90AB1
UniProt Synonym Gene Names
HSP90B; HSPC2; HSPCB; HSP 90; HSP 84; HSP84
UniProt Entry Name
HS90B_HUMAN

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Product Notes

The HSP90AB1 hsp90ab1 (Catalog #AAA806919) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human HSP90 beta, native sequence reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Hsp90 beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB) control, Chaperone assays, Inhibitor/binding assays, ELISA (EIA) reference standard, Co-IP. Researchers should empirically determine the suitability of the HSP90AB1 hsp90ab1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hsp90 beta, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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