Creatine Kinase MB Active Protein | CKMB active protein
Creatine Kinase MB Isoenzyme, Human Heart
Synonyms
Creatine Kinase MB; Creatine Kinase MB Isoenzyme; Human Heart; CKMB; CK-MB; CKMB active protein
Host
Human Heart
Form/Format
0.2 micron filtered solution in 10 mM tris-succinate, 2 mM DTT , 2 mM EDTA, 175 mM sodium chloride, pH 7.0 with glycerol added to 50% (v/v)
CAS Number
9001-15-4
E.C Number
2.7.3.2
Appearance
Clear, ligth brown solution
Activity
1,590 U/mL (Dimension® Clinical Chemistry System)
Unit definition
One unit wil catalyze the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37°C.
Protein
33 mg/mL (Coomasie)
Specific activity
48 U/mg protein
Electrophoresis
≥ 99% CKMB (Helena Quick Gel® CK)
Contaminants
GOT < 1%
LDH < 1%
LDH < 1%
Country of origin
United States of America
Note: Donor material originates from TSE, CJD and vCJD- free countries, and mandatorily reports requirements for occurrence of these diseases
Note: Donor material originates from TSE, CJD and vCJD- free countries, and mandatorily reports requirements for occurrence of these diseases
Handling
Handle as a potentially hazardous substance
Recovery
Centrifuge briefly to ensure complete recovery.
Preparation and Storage
Store at -20°C
Related Product Information for CKMB active protein
MyBioSource produces human cardiac Creatine Kinase MB (CK-MB) isoenzyme for research, life science and use as a control or calibrator for manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Creatine Kinase is one of the most important myocardial markers (in spite of not being altogether cardiac-specific), with well-established roles in confirming acute myocardial infarction (AMI). It can also used for monitoring reperfusion during thrombolytic therapy following AMI. Testing is performed when the total Creatine Phosphokinase (CPK) level is elevated. Isoenzyme testing can help differentiate the source of the damaged tissue. Human CPK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Creatine Kinase MM, BB, and MB isoenzymes exist.
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Creatine Kinase is one of the most important myocardial markers (in spite of not being altogether cardiac-specific), with well-established roles in confirming acute myocardial infarction (AMI). It can also used for monitoring reperfusion during thrombolytic therapy following AMI. Testing is performed when the total Creatine Phosphokinase (CPK) level is elevated. Isoenzyme testing can help differentiate the source of the damaged tissue. Human CPK enzyme consists of two subunits, which can be either B (brain type) or M (muscle type). Three different isoenzymes: Creatine Kinase MM, BB, and MB isoenzymes exist.
Product Categories/Family for CKMB active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84,000
Uniprot Description
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
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Product Notes
The CKMB (Catalog #AAA170403) is an Active Protein produced from Human Heart and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Creatine Kinase MB, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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