Human Zinc finger C3H1 domain-containing protein (ZFC3H1) ELISA Kit | ZFC3H1 elisa kit

Human Zinc finger C3H1 domain-containing protein (ZFC3H1) ELISA Kit

Cat. Num. AAA286595

• Gene Names: ZFC3H1; CSRC2; PSRC2; CCDC131
• Reactivity: Human
• Synonyms: Zinc finger C3H1 domain-containing protein (ZFC3H1); Human Zinc finger C3H1 domain-containing protein (ZFC3H1) ELISA Kit; CCDC131; DKFZp686A0722; KIAA0546; MGC23401; MGC90200; PSRC2; coiled-coil domain containing 131; proline/serine-rich coiled-coil 2; ZFC3H1 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human ZFC3H1. No significant cross-reactivity or interference between Human ZFC3H1 and analogues was observed.
• Sequence Length: 1989

• Assay Type: Quantitive Sandwich
• Samples: Serum, Plasma, Other Biological Fluids
• Detection Wavelength: 450 nm
• Intra-assay Precision (Precision within an assay): Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
• Inter-assay Precision (Precision between assays): Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
• CV (%): = SD/meanX100
• Intra-Assay: CV
• Inter-Assay: CV
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for ZFC3H1 elisa kit

Description: This assay employs a two-site sandwich ELISA to quantitate ZFC3H1 in samples. An antibody specific for ZFC3H1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ZFC3H1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ZFC3H1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ZFC3H1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Overview: ZFC3H1 May be involved in transcriptional regulation.Contains 1 C3H1-type zinc finger. Contains 6 HAT repeats.Contains 5 TPR repeats.
A zinc finger protein is a DNA-binding protein domain consisting of zinc fingers ranging from two in the Drosophila regulator ADR1, the more common three in mammalian Sp1 up to nine in TFIIIA. They occur in nature as the part of transcription factors conferring DNA sequence specificity as the DNA-binding domain. They have also found use in protein engineering due to their modularity and have prospects as components of tools for use in therapeutic gene modulation and zinc finger nucleases. Zinc finger protein consists of anti-parallel hairpin motif. It consists of 2 beta strands, one alpha helix and a hairpin structure.

NCBI and Uniprot Product Information

• NCBI GI #: 87116683
• NCBI GeneID: 196441
• NCBI Accession #: NP_659419.3
• NCBI GenBank Nucleotide #: NM_144982.4
• UniProt Accession #: O60293; Q6GMU1; Q6P2S9; Q6ZV36; Q96BE7
• Molecular Weight: 37,841 Da
• NCBI Official Full Name: zinc finger C3H1 domain-containing protein
• NCBI Official Synonym Full Names: zinc finger C3H1-type containing
• NCBI Official Symbol: ZFC3H1
• NCBI Official Synonym Symbols: CSRC2; PSRC2; CCDC131
• NCBI Protein Information: zinc finger C3H1 domain-containing protein
• UniProt Protein Name: Zinc finger C3H1 domain-containing protein
• Protein Family: Zinc finger C3H1 domain-containing protein
• UniProt Gene Name: ZFC3H1
• UniProt Synonym Gene Names: CCDC131; KIAA0546; PSRC2

Uniprot Description

Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.