Typical Testing Data/Standard Curve (for reference only)
()
Human Transient Receptor Potential Cation Channel Subfamily M Member 1 (TRPM1) ELISA Kit | TRPM1 elisa kit
Human Transient Receptor Potential Cation Channel Subfamily M Member 1 (TRPM1) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
()
Typical Testing Data/Standard Curve (for reference only)
()
Background/Introduction: Transient receptor potential cation channel subfamily M member 1 is a protein similar to the transient receptor potential (Trp) calcium channel family members. The expression of this protein is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Uniprot Description
TRPM1: a transient receptor potential (TRP) ion channel. TRP voltage-independent calcium-permeable cation channels are divided into six subfamilies, two of which (TRPC and TRPM) have members that are widely expressed. Its expression is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis.
Protein type: Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 15q13.3
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: calcium channel activity
Biological Process: metabotropic glutamate receptor signaling pathway; transport; visual perception
Disease: Night Blindness, Congenital Stationary, Type 1c
Research Articles on TRPM1
Similar Products
Product Notes
The Human TRPM1 trpm1 (Catalog #AAA9713799) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9713799 ELISA Kit recognizes Human TRPM1. It is sometimes possible for the material contained within the vial of "Transient Receptor Potential Cation Channel Subfamily M Member 1 (TRPM1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
