Typical Standard Curve

Human TMPRSS6 (Transmembrane protease serine 6) ELISA Kit | TMPRSS6 elisa kit

Human TMPRSS6 (Transmembrane protease serine 6)

Gene Names

TMPRSS13; MSP; MSPL; MSPS; TMPRSS11

Reactivity

Human

Synonyms

TMPRSS6 (Transmembrane protease serine 6); Human TMPRSS6 (Transmembrane protease serine 6); TMPRSS6 elisa kit

Ordering
Cat. Num. AAA766117 For Research Use Only!

Reactivity

Human

Specificity

This assay has high sensitivity and excellent specificity for detection of TMPRSS6 . No significant cross-reactivity or interference between TMPRSS6 and analogues was observed.

Sequence Length

558

Samples

Serum, plasma and other biological fluids.

Assay Type

Sandwich ELISA, Double Antibody

Detection Range

125-8000pg/ml

Sensitivity

75pg/ml

Intra-assay Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level TMPRSS6were tested 20 times on one plate, respectively. Intra-Assay: CV<8%

Inter-assay Precision

Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level TMPRSS6were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%

Preparation and Storage

4 degree C for 6 months

Typical Standard Curve

Related Product Information for TMPRSS6 elisa kit

Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti- TMPRSS6antibody was pre-coated onto 96-well plates. And the biotin conjugated anti- TMPRSS6 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and wash with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the TMPRSS6 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of TMPRSS6 can be calculated.

NCBI and Uniprot Product Information

NCBI GI #

28371868

NCBI GeneID

84000

Molecular Weight

52,560 Da

NCBI Official Full Name

transmembrane protease serine 6

NCBI Official Synonym Full Names

transmembrane protease, serine 13

NCBI Official Symbol

TMPRSS13

NCBI Official Synonym Symbols

MSP; MSPL; MSPS; TMPRSS11

NCBI Protein Information

transmembrane protease serine 13

UniProt Protein Name

Transmembrane protease serine 13

Protein Family

Transmembrane protease serine

UniProt Gene Name

TMPRSS13

UniProt Synonym Gene Names

MSP; TMPRSS11; Mosaic serine protease

UniProt Entry Name

TMPSD_HUMAN

NCBI Description

This gene encodes a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

TMPRSS13: a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Protein type: Protease; EC 3.4.21.-; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: integral to membrane

Molecular Function: scavenger receptor activity; serine-type endopeptidase activity

Biological Process: proteolysis; receptor-mediated endocytosis

Research Articles on TMPRSS6

1. study demonstrates that two cellular serine proteases, DESC1 and MSPL, activate influenza viruses and emerging coronaviruses in cell culture and, because of their expression in human lung tissue, might promote viral spread in the infected host

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Product Notes

The Human TMPRSS6 tmprss13 (Catalog #AAA766117) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA766117 ELISA Kit recognizes Human TMPRSS6. It is sometimes possible for the material contained within the vial of "TMPRSS6 (Transmembrane protease serine 6), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Human TMPRSS6 (Transmembrane protease serine 6) ELISA Kit | TMPRSS6 elisa kit