Human TAF10 RNA polymerase II, TATA box binding protein (TBP) -associated factor, 30kDa ELISA Kit | TAF10 elisa kit
Human Transcription initiation factor TFIID subunit 10, TAF10 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs. [provided by RefSeq, Jul 2008]
Uniprot Description
TAF10: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Belongs to the TAF10 family.
Protein type: Transcription initiation complex; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 11p15.3
Cellular Component: nucleoplasm; transcription factor TFIID complex; PCAF complex; perinuclear region of cytoplasm; cytoplasm; nucleus
Molecular Function: protein binding; histone acetyltransferase activity; enzyme binding; transcription coactivator activity; estrogen receptor binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; viral reproduction; regulation of transcription, DNA-dependent; transcription initiation; RNA elongation from RNA polymerase II promoter; gene expression; protein homooligomerization; histone deubiquitination
Research Articles on TAF10
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Product Notes
The Human TAF10 taf10 (Catalog #AAA9341955) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9341955 ELISA Kit recognizes Human TAF10. It is sometimes possible for the material contained within the vial of "TAF10 RNA polymerase II, TATA box binding protein (TBP) -associated factor, 30kDa, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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