Human Semaphorin 4C (SEMA4C) ELISA Kit | SEMA4C elisa kit
Human Semaphorin 4C (SEMA4C) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SEMA4C: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. Belongs to the semaphorin family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q11.2
Cellular Component: postsynaptic membrane; extracellular space; synaptic vesicle membrane; postsynaptic density; integral to membrane; cell junction
Molecular Function: receptor activity
Biological Process: cell migration in hindbrain; muscle cell differentiation; neural tube closure; cerebellum development; positive regulation of stress-activated MAPK cascade
Research Articles on SEMA4C
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Product Notes
The Human SEMA4C sema4c (Catalog #AAA9301399) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9301399 ELISA Kit recognizes Human SEMA4C. It is sometimes possible for the material contained within the vial of "Semaphorin 4C (SEMA4C), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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