Human Semaphorin 3F (SEMA3F) ELISA Kit | SEMA3F elisa kit
Human Semaphorin 3F (SEMA3F) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.[supplied by OMIM, Mar 2008]
Uniprot Description
SEMA3F: May play a role in cell motility and cell adhesion. Belongs to the semaphorin family.
Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p21.3
Cellular Component: extracellular space; membrane
Molecular Function: chemorepellent activity; receptor activity
Biological Process: axon extension involved in axon guidance; axon guidance; facial nerve structural organization; trigeminal nerve structural organization; branchiomotor neuron axon guidance; negative chemotaxis; nerve development; negative regulation of axon extension involved in axon guidance
Research Articles on SEMA3F
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Product Notes
The Human SEMA3F sema3f (Catalog #AAA9309445) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9309445 ELISA Kit recognizes Human SEMA3F. It is sometimes possible for the material contained within the vial of "Semaphorin 3F (SEMA3F), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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