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Human Selenium Binding Protein 1 (SELENBP1) ELISA Kit | SELENBP1 elisa kit

Human Selenium Binding Protein 1 (SELENBP1) ELISA Kit

Gene Names
SELENBP1; MTO; LPSB; SP56; hSBP; EHMTO; SBP56; HEL-S-134P
Reactivity
Human
Synonyms
Selenium Binding Protein 1 (SELENBP1); Human Selenium Binding Protein 1 (SELENBP1) ELISA Kit; SELENBP1; RP11-126K1.7; FLJ13813; LPSB; SP56; hSBP; hSP56; SELENBP1 elisa kit
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For Research Use Only!
Reactivity
Human
Specificity
Human Selenium binding protein 1 (SELENBP1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SELENBP1. No significant cross-reactivity or interference between Human SELENBP1 and analogues was observed.
Sequence Length
472
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

(Fig.1. Human Selenium binding protein 1 (SELENBP1) Standard Curve.)

Related Product Information for SELENBP1 elisa kit
Description: This Human Selenium binding protein 1 (SELENBP1) ELISA Kit employs a two-site sandwich ELISA to quantitate SELENBP1 in samples. An antibody specific for SELENBP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SELENBP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SELENBP1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SELENBP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Background: protein belongs to the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. It has been proposed that the effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins. The exact function of this gene is not known. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Methanethiol oxidase
NCBI Official Synonym Full Names
selenium binding protein 1
NCBI Official Symbol
SELENBP1
NCBI Official Synonym Symbols
MTO; LPSB; SP56; hSBP; EHMTO; SBP56; HEL-S-134P
NCBI Protein Information
methanethiol oxidase; selenium-binding protein 1
UniProt Protein Name
Selenium-binding protein 1
Protein Family
UniProt Gene Name
SELENBP1
UniProt Synonym Gene Names
SBP; SBP56; SP56
UniProt Entry Name
SBP1_HUMAN

NCBI Description

This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

Uniprot Description

SELENBP1: Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. Belongs to the selenium-binding protein family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: extracellular space; membrane; nucleolus; cytosol

Molecular Function: selenium binding; protein binding

Biological Process: protein transport

Research Articles on SELENBP1

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Product Notes

The Human SELENBP1 selenbp1 (Catalog #AAA9714385) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714385 ELISA Kit recognizes Human SELENBP1. It is sometimes possible for the material contained within the vial of "Selenium Binding Protein 1 (SELENBP1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.
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