Typical Testing Data/Standard Curve (for reference only)
Human SARM1 (Sterile alpha and TIR motif-containing protein 1) ELISA Kit | SARM1 elisa kit
Human SARM1 (Sterile alpha and TIR motif-containing protein 1) ELISA Kit
Gene Names
SARM1; SARM; SAMD2; MyD88-5
Reactivity
Human
Synonyms
SARM1 (Sterile alpha and TIR motif-containing protein 1); Human SARM1 (Sterile alpha and TIR motif-containing protein 1) ELISA Kit; SARM1; NAD(+) hydrolase SARM1; NADase SARM1; hSARM1; Sterile alpha and Armadillo repeat protein; Sterile alpha and TIR motif-containing protein 1; Sterile alpha motif domain-containing protein 2; MyD88-5; SAM domain-containing protein 2; Tir-1 homolog; HsTIR; SARM1 elisa kit
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of SARM1. No significant cross-reactivity or interference between SARM1 and analogues was observed.
Samples
Serum, plasma, tissue homogenates and other biological fluids
Assay Type
Quantitative Sandwich
Detection Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Intra-assay Precision
CV<8%
Inter-assay Precision
CV<10%
Preparation and Storage
Store at 2-8 degree C for 6 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for SARM1 elisa kit
Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the target amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of target can be calculated.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,337 Da
NCBI Official Full Name
sterile alpha and TIR motif-containing protein 1
NCBI Official Synonym Full Names
sterile alpha and TIR motif containing 1
NCBI Official Symbol
SARM1
NCBI Official Synonym Symbols
SARM; SAMD2; MyD88-5
NCBI Protein Information
sterile alpha and TIR motif-containing protein 1; tir-1 homolog; SAM domain-containing protein 2; sterile alpha and Armadillo repeat protein; sterile alpha motif domain-containing protein 2; sterile alpha and HEAT/Armadillo motif protein, ortholog of Dros
UniProt Protein Name
Sterile alpha and TIR motif-containing protein 1
Protein Family
UniProt Gene Name
SARM1
UniProt Synonym Gene Names
KIAA0524; SAMD2; SARM; MyD88-5; SAM domain-containing protein 2
UniProt Entry Name
SARM1_HUMAN
Uniprot Description
SARM1: Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17q11
Cellular Component: microtubule; mitochondrion; axon; cytoplasm; dendrite; extrinsic to mitochondrial outer membrane; synapse; cytosol; cell junction
Biological Process: regulation of apoptosis; MyD88-independent toll-like receptor signaling pathway; regulation of dendrite morphogenesis; response to glucose stimulus; toll-like receptor signaling pathway; innate immune response; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway
Research Articles on SARM1
Similar Products
Product Notes
The Human SARM1 sarm1 (Catalog #AAA7612187) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7612187 ELISA Kit recognizes Human SARM1. It is sometimes possible for the material contained within the vial of "SARM1 (Sterile alpha and TIR motif-containing protein 1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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