Human Retinol-Binding Protein (RBP) ELISA Kit | RBP elisa kit

Human Retinol-Binding Protein (RBP) ELISA Kit

Cat. Num. AAA3801276

• Gene Names: RBP3; IRBP; RBPI; RP66; D10S64; D10S65; D10S66
• Reactivity: Human
• Synonyms: Retinol-Binding Protein (RBP); Human Retinol-Binding Protein (RBP) ELISA Kit; RBP elisa kit

• Reactivity: Human
• Sequence Length: 1246

• Sensitivity: 0.1ug/mL

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for RBP elisa kit

Intended Uses: This RBP ELISA kit is intended Laboratory for Research use only. The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration of RBP in the sample, this RBP ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus RBP concentration. The concentration of DYKDDDDK -TAG in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 307075
• NCBI GeneID: 5949
• NCBI Official Full Name: retinol-binding protein
• NCBI Official Synonym Full Names: retinol binding protein 3
• NCBI Official Symbol: RBP3
• NCBI Official Synonym Symbols: IRBP; RBPI; RP66; D10S64; D10S65; D10S66
• NCBI Protein Information: retinol-binding protein 3
• Protein Family: Receptor binding protein

NCBI Description

Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008]