Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Retinoic acid receptor responder protein 2 (RARRES2) Standard Curve.)
Human Retinoic Acid Receptor Responder Protein 2 (RARRES2) ELISA Kit | RARRES2 elisa kit
Human Retinoic Acid Receptor Responder Protein 2 (RARRES2) ELISA Kit
Gene Names
RARRES2; TIG2; HP10433
Reactivity
Human
Synonyms
Retinoic Acid Receptor Responder Protein 2 (RARRES2); Human Retinoic Acid Receptor Responder Protein 2 (RARRES2) ELISA Kit; RARRES2; HP10433; TIG2; chemerin; RARRES2 elisa kit
Reactivity
Human
Specificity
Human Retinoic acid receptor responder protein 2 (RARRES2) ELISA Kit has high sensitivity and excellent specificity for detection of Human RARRES2. No significant cross-reactivity or interference between Human RARRES2 and analogues was observed.
Sequence Length
163
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Retinoic acid receptor responder protein 2 (RARRES2) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Retinoic acid receptor responder protein 2 (RARRES2) Standard Curve.)
Related Product Information for RARRES2 elisa kit
Description: This Human Retinoic acid receptor responder protein 2 (RARRES2) ELISA Kit employs a two-site sandwich ELISA to quantitate RARRES2 in samples. An antibody specific for RARRES2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RARRES2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RARRES2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RARRES2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: Chemerin is a novel protein identified as the natural ligand of ChemR23 (chemerinR), a previously orphan G protein-coupled receptor expressed in immature dendritic cells and macrophages. It is a member of the Cystatin superfamily. Chemerin is synthesized as a 163 aa secreted precursor, prochemerin, which contains a hydrophobic 20 aa N-terminal sequence, an intervening 137 aa Cystatin fold-containing domain, and a six aa C-terminal prosegment. It is activated by proteases of the coagulation, fibrinolytic, and inflammatory cascades and converted into a full agonist of chemerinR by proteolytic removal of the last six amino acids.Chemerin is a chemoattractant for cells bearing the Chem R23 receptor, including plasmacytoid dendritic cells and tissue macrophages.
Background: Chemerin is a novel protein identified as the natural ligand of ChemR23 (chemerinR), a previously orphan G protein-coupled receptor expressed in immature dendritic cells and macrophages. It is a member of the Cystatin superfamily. Chemerin is synthesized as a 163 aa secreted precursor, prochemerin, which contains a hydrophobic 20 aa N-terminal sequence, an intervening 137 aa Cystatin fold-containing domain, and a six aa C-terminal prosegment. It is activated by proteases of the coagulation, fibrinolytic, and inflammatory cascades and converted into a full agonist of chemerinR by proteolytic removal of the last six amino acids.Chemerin is a chemoattractant for cells bearing the Chem R23 receptor, including plasmacytoid dendritic cells and tissue macrophages.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
retinoic acid receptor responder protein 2
NCBI Official Synonym Full Names
retinoic acid receptor responder 2
NCBI Official Symbol
RARRES2
NCBI Official Synonym Symbols
TIG2; HP10433
NCBI Protein Information
retinoic acid receptor responder protein 2
UniProt Protein Name
Retinoic acid receptor responder protein 2
Protein Family
UniProt Gene Name
RARRES2
UniProt Synonym Gene Names
TIG2
UniProt Entry Name
RARR2_HUMAN
NCBI Description
This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrobial protein with activity against bacteria and fungi. [provided by RefSeq, Nov 2014]
Uniprot Description
RARRES2: Inhibited in psoriatic lesions. Activated by tazarotene in skin rafts and in the epidermis of psoriatic lesions.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 7q36.1
Cellular Component: extracellular matrix; extracellular region
Molecular Function: protein binding; receptor binding
Biological Process: positive regulation of chemotaxis; in utero embryonic development; brown fat cell differentiation; positive regulation of fat cell differentiation; positive regulation of protein amino acid phosphorylation; inflammatory response; retinoid metabolic process; chemotaxis; embryonic gut development; regulation of lipid catabolic process
Research Articles on RARRES2
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Product Notes
The Human RARRES2 rarres2 (Catalog #AAA9714639) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714639 ELISA Kit recognizes Human RARRES2. It is sometimes possible for the material contained within the vial of "Retinoic Acid Receptor Responder Protein 2 (RARRES2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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