Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Ras-related protein Rab-1A (RAB1A) Standard Curve.)
Human Ras-Related Protein Rab-1A (RAB1A) ELISA Kit | RAB1A elisa kit
Human Ras-Related Protein Rab-1A (RAB1A) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Ras-related protein Rab-1A (RAB1A) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Ras-related protein Rab-1A (RAB1A) Standard Curve.)
Background: RAB1A encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. RAB1 recruited p115 to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum (ER), where it interacted with a select set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus.RAB1-regulated assembly of functional effector-SNARE complexes defines a conserved molecular mechanism to coordinate recognition between subcellular compartments.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008]
Uniprot Description
RAB1A: Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, monomeric; G protein, monomeric, Rab; G protein
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; early endosome; melanosome; cytosol
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding
Biological Process: ER to Golgi vesicle-mediated transport; cell migration; endocytosis; virus assembly; melanosome transport; vesicle-mediated transport; growth hormone secretion; intracellular protein transport; defense response to bacterium; vesicle transport along microtubule; autophagy; cilium biogenesis; mitotic cell cycle; Rab protein signal transduction; Golgi organization and biogenesis; autophagic vacuole formation
Research Articles on RAB1A
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Product Notes
The Human RAB1A rab1a (Catalog #AAA9714658) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714658 ELISA Kit recognizes Human RAB1A. It is sometimes possible for the material contained within the vial of "Ras-Related Protein Rab-1A (RAB1A), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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