Human RAB23, member RAS oncogene family ELISA Kit | RAB23 elisa kit
Human Ras-related protein Rab-23, RAB23 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
RAB23: Defects in RAB23 are the cause of acrocephalopolysyndactyly type 2 (ACPS2). A syndrome characterized by craniosynostosis, polysyndactyly, obesity, and cardiac defects. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 6p11
Cellular Component: phagocytic vesicle membrane; cytoplasm; plasma membrane; endosome membrane; autophagic vacuole; phagocytic vesicle
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding
Biological Process: negative regulation of proteolysis; protein transport; spinal cord dorsal/ventral patterning; cilium biogenesis; cellular defense response; embryonic digit morphogenesis; Rab protein signal transduction; negative regulation of transcription factor import into nucleus; autophagic vacuole formation; regulation of smoothened signaling pathway
Disease: Carpenter Syndrome 1
Research Articles on RAB23
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Product Notes
The Human RAB23 rab23 (Catalog #AAA9335801) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9335801 ELISA Kit recognizes Human RAB23. It is sometimes possible for the material contained within the vial of "RAB23, member RAS oncogene family, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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