Human RAB13, member RAS oncogene family ELISA Kit | RAB13 elisa kit
Human Ras-related protein Rab-13, RAB13 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013]
Uniprot Description
RAB13: Could participate in polarized transport, in the assembly and/or the activity of tight junctions. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein; G protein, monomeric, Rab; G protein, monomeric
Chromosomal Location of Human Ortholog: 1q21.2
Cellular Component: Golgi apparatus; neuron projection; tight junction; cytoplasmic vesicle membrane; recycling endosome membrane; trans-Golgi network; recycling endosome; lamellipodium; endocytic vesicle; cytoplasm; plasma membrane; cytoplasmic vesicle; lateral plasma membrane
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding
Biological Process: intracellular protein transport; cellular response to insulin stimulus; metabolic process; cortical actin cytoskeleton organization and biogenesis; endocytic recycling; Rab protein signal transduction; endosome transport; neurite development
Research Articles on RAB13
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Product Notes
The Human RAB13 rab13 (Catalog #AAA9331497) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331497 ELISA Kit recognizes Human RAB13. It is sometimes possible for the material contained within the vial of "RAB13, member RAS oncogene family, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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