Human Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12) ELISA Kit | P2RY12 elisa kit

Human Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12) ELISA Kit

Cat. Num. AAA451641

• Gene Names: P2RY12; HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
• Reactivity: Human
• Synonyms: Purinergic Receptor P2Y; G Protein Coupled 12 (P2RY12); Human Purinergic Receptor P2Y; G Protein Coupled 12 (P2RY12) ELISA Kit; ADPG-R; HORK3; P2T(AC); P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; SP1999; ADP-glucose receptor; P2Y12 platelet ADP receptor; P2RY12 elisa kit

• Reactivity: Human
• Sequence Length: 342

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: 0.063ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 12232483
• NCBI GeneID: 64805
• NCBI Accession #: NP_073625.1
• NCBI GenBank Nucleotide #: NM_022788.4
• UniProt Accession #: Q9H244; Q546J7; D3DNJ5
• Molecular Weight: 39,439 Da
• NCBI Official Full Name: P2Y purinoceptor 12
• NCBI Official Synonym Full Names: purinergic receptor P2Y12
• NCBI Official Symbol: P2RY12
• NCBI Official Synonym Symbols: HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
• NCBI Protein Information: P2Y purinoceptor 12
• UniProt Protein Name: P2Y purinoceptor 12
• Protein Family: P2Y purinoceptor
• UniProt Gene Name: P2RY12
• UniProt Synonym Gene Names: HORK3; P2Y12; ADPG-R; P2Y(ADP)

NCBI Description

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Uniprot Description

Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.