Human POM121 membrane glycoprotein (rat) ELISA Kit | POM121 elisa kit
Human Nuclear envelope pore membrane protein POM 121, POM121 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013]
Uniprot Description
POM121: a single-pass membrane protein that is an essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). Stably associated with the NPC throughout interphase and with the endoplasmic reticulum during metaphase. Contains F-X-F-G repeats. Belongs to the POM121 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Nucleoporin
Chromosomal Location of Human Ortholog: 7q11.23
Cellular Component: endoplasmic reticulum membrane; nuclear membrane; nuclear envelope; nuclear pore
Biological Process: protein transport; mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; hexose transport; carbohydrate metabolic process; mitotic nuclear envelope disassembly; viral transcription; gene expression; pathogenesis; glucose transport; viral infectious cycle; mitotic cell cycle; transmembrane transport
Research Articles on POM121
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Product Notes
The Human POM121 pom121 (Catalog #AAA9327760) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327760 ELISA Kit recognizes Human POM121. It is sometimes possible for the material contained within the vial of "POM121 membrane glycoprotein (rat), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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