Typical Testing Data/Standard Curve (for reference only)
Human Phospholipase A2, Group X ELISA Kit | Pla2g10 elisa kit
Human Phospholipase A2, Group X ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the phospholipase A2 family of lipolytic enzymes that hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. The encoded protein undergoes proteolytic processing to generate a calcium-dependent enzyme that plays pivotal roles in the liberation of arachidonic acid from membrane phospholipids leading to the production of various inflammatory lipid mediators, such as prostaglandins. In response to myocardial ischemia/reperfusion, mice lacking the encoded protein display a reduction in myocardial infarct size partly through the suppression of neutorphil cytotoxic activities. Alternative splicing results in multiple transcript variants encoding different isoforms. All of these isoforms may undergo similar processing to generate the mature protein. [provided by RefSeq, Jul 2015]
Uniprot Description
PLA2G10: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine. Belongs to the phospholipase A2 family.
Protein type: Secreted, signal peptide; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Motility/polarity/chemotaxis; Secreted; Phospholipase; Lipid Metabolism - arachidonic acid; Lipid Metabolism - linoleic acid; Cell development/differentiation; EC 3.1.1.4; Lipid Metabolism - alpha-linolenic acid
Cellular Component: extracellular region
Molecular Function: phospholipase A2 activity; hydrolase activity; metal ion binding; calcium ion binding; phospholipase activity
Biological Process: axon guidance; cholesterol homeostasis; phospholipid metabolic process; lysophospholipid transport; regulation of macrophage activation; negative regulation of transcription factor activity; positive regulation of cellular protein metabolic process; positive regulation of prostaglandin secretion; lipid metabolic process; lipid catabolic process
Research Articles on Pla2g10
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Product Notes
The Human Pla2g10 pla2g10 (Catalog #AAA3804783) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3804783 ELISA Kit recognizes Human Pla2g10. It is sometimes possible for the material contained within the vial of "Phospholipase A2, Group X, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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