Human Peroxiredoxin 2 (PRDX2) ELISA Kit | PRDX2 elisa kit

Human Peroxiredoxin 2 (PRDX2) ELISA Kit

Cat. Num. AAA451304

• Gene Names: PRDX2; PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a
• Reactivity: Human
• Synonyms: Peroxiredoxin 2 (PRDX2); Human Peroxiredoxin 2 (PRDX2) ELISA Kit; PRP NKEFB PRXII TDPX1 TSA Thioredoxin-Dependent Peroxide Reductase 1 Thiol-Specific Antioxidant 1 Natural Killer-Enhancing Factor B Thioredoxin Peroxidase 1 Torin; PRDX2 elisa kit

• Reactivity: Human
• Sequence Length: 198

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.781-50ng/mL
• Sensitivity: 0.35ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 32189392
• NCBI GeneID: 7001
• NCBI Accession #: NP_005800.3
• NCBI GenBank Nucleotide #: NM_005809.5
• UniProt Accession #: P32119; P31945; P32118; P35701; Q6FHG4; Q92763; Q9UC23; A8K0C0
• Molecular Weight: 15,819 Da
• NCBI Official Full Name: peroxiredoxin-2
• NCBI Official Synonym Full Names: peroxiredoxin 2
• NCBI Official Symbol: PRDX2
• NCBI Official Synonym Symbols: PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a
• NCBI Protein Information: peroxiredoxin-2
• UniProt Protein Name: Peroxiredoxin-2
• Protein Family: Peroxiredoxin
• UniProt Gene Name: PRDX2
• UniProt Synonym Gene Names: NKEFB; TDPX1; NKEF-B; TSA

NCBI Description

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]

Uniprot Description

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.