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Typical Testing Data/Standard Curve (for reference only)

Human NRXN3 (Neurexin-3) ELISA Kit | NRXN3 elisa kit

Human NRXN3 (Neurexin-3) ELISA Kit

Gene Names
NRXN3; C14orf60
Reactivity
Human
Synonyms
NRXN3 (Neurexin-3); Human NRXN3 (Neurexin-3) ELISA Kit; NRXN3; Neurexin-3; Neurexin III-alpha; Neurexin-3-alpha; C14orf60; KIAA0743; NRXN3 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of NRXN3. No significant cross-reactivity or interference between NRXN3 and analogues was observed.
Samples
Serum, plasma, tissue homogenates and other biological fluids
Assay Type
Quantitative Sandwich
Detection Range
31.25-2000pg/ml
Sensitivity
18.75pg/ml
Intra-assay Precision
CV<8%
Inter-assay Precision
CV<10%
Preparation and Storage
Store at 2-8 degree C for 6 months

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for NRXN3 elisa kit
Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Capture antibody was pre-coated onto 96-well plates. And the biotin conjugated antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the target amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of target can be calculated.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
180,599 Da
NCBI Official Full Name
neurexin 3 isoform 1
NCBI Official Synonym Full Names
neurexin 3
NCBI Official Symbol
NRXN3
NCBI Official Synonym Symbols
C14orf60
NCBI Protein Information
neurexin 3
UniProt Protein Name
Neurexin-3
Protein Family
UniProt Gene Name
NRXN3
UniProt Synonym Gene Names
C14orf60; KIAA0743
UniProt Entry Name
NRX3A_HUMAN

NCBI Description

This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]

Uniprot Description

NRXN3: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. Belongs to the neurexin family. 7 isoforms of the human protein are produced by alternative promoter.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 14q31

Cellular Component: integral to plasma membrane; integral to membrane

Molecular Function: metal ion binding; calcium channel regulator activity; receptor activity; cell adhesion molecule binding

Biological Process: positive regulation of synaptogenesis; axon guidance; synaptic transmission; synaptogenesis; neurotransmitter secretion; adult behavior; neuron adhesion; learning; angiogenesis; social behavior

Research Articles on NRXN3

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Product Notes

The Human NRXN3 nrxn3 (Catalog #AAA7612158) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7612158 ELISA Kit recognizes Human NRXN3. It is sometimes possible for the material contained within the vial of "NRXN3 (Neurexin-3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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