Human Neogenin 1 (NEO1) ELISA Kit | NEO1 elisa kit

Human Neogenin 1 (NEO1) ELISA Kit

Cat. Num. AAA455199

• Gene Names: NEO1; NGN; IGDCC2; NTN1R2
• Reactivity: Human
• Synonyms: Neogenin 1 (NEO1); Human Neogenin 1 (NEO1) ELISA Kit; NGN; IGDCC2; Immunoglobulin Superfamily; DCC Subclass Member 2; NEO1 elisa kit

• Reactivity: Human
• Sequence Length: 1408

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: 0.063ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 290656011
• NCBI GeneID: 4756
• NCBI Accession #: NP_001166094.1
• NCBI GenBank Nucleotide #: NM_001172623.1
• UniProt Accession #: Q92859; O00340; Q17RX1; B7ZKM9; B7ZKN0
• Molecular Weight: 158,827 Da
• NCBI Official Full Name: neogenin isoform 2
• NCBI Official Synonym Full Names: neogenin 1
• NCBI Official Symbol: NEO1
• NCBI Official Synonym Symbols: NGN; IGDCC2; NTN1R2
• NCBI Protein Information: neogenin
• UniProt Protein Name: Neogenin
• Protein Family: Neogenin
• UniProt Gene Name: NEO1
• UniProt Synonym Gene Names: IGDCC2; NGN

NCBI Description

This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Uniprot Description

Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response.