Testing Data
(The TFact MYSM1 DNA-Binding ELISA detects active MYSM1 in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
Human MYSM1 ELISA Kit | MYSM1 elisa kit
MYSM1 TFact DNA-Binding ELISA Kit
Testing Data
(The TFact MYSM1 DNA-Binding ELISA detects active MYSM1 in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
Testing Data
(The TFact MYSM1 DNA-Binding ELISA detects active MYSM1 in HepG2 and MCF7 Nuclear Extract. The HepG2 and MCF7 cells were grown 3 days in DMEM with 10% FBS and harvested for nuclear extract. )
NCBI and Uniprot Product Information
Uniprot Description
MYSM1: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Belongs to the peptidase M67A family. MYSM1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.19.-; Protease; Ubiquitin conjugating system; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 1p32.1
Cellular Component: nucleoplasm; nucleus; plasma membrane
Molecular Function: DNA binding; histone binding; metal ion binding; metallopeptidase activity; protein complex binding; thiol-dependent ubiquitin-specific protease activity; transcription coactivator activity
Biological Process: chromatin remodeling; pigmentation; positive regulation of transcription from RNA polymerase II promoter; protein deubiquitination; regulation of cell migration; regulation of hair follicle development; transcription, DNA-dependent
Research Articles on MYSM1
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Product Notes
The Human MYSM1 mysm1 (Catalog #AAA9502298) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502298 ELISA Kit recognizes Human MYSM1. It is sometimes possible for the material contained within the vial of "MYSM1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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