Human myosin heavy chain, MHC ELISA Kit | MHC elisa kit
Human myosin heavy chain, MHC ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Muscle contraction.
Subunit structure: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
Subcellular location: Cytoplasm › myofibril. Note: Thick filaments of the myofibrils.
Tissue specificity: Expressed in larval and adult muscles. Isoforms containing exon 9a are expressed in indirect flight muscles, exons 9a and 9b are expressed in jump muscles, exons 9b and 9c are expressed in other larval and adult muscles. Ref.2
Domain: Alternative splicing exons contribute to the specialized contractile activities of different muscle types. Exon 3 encodes the hydrophobic pocket adjacent to the ATP-binding site, exon 9 is adjacent to the actin-binding domain, exon 11 is involved in actin-binding, exon 15 in the S2 hinge and exons 18 and 19 the non-coiled tail region.Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
Sequence similarities: Contains 1 IQ domain.Contains 1 myosin head-like domain.
Research Articles on MHC
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Product Notes
The Human MHC mhc (Catalog #AAA9301904) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9301904 ELISA Kit recognizes Human MHC. It is sometimes possible for the material contained within the vial of "myosin heavy chain, MHC, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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