Human Myeloid Progenitor Inhibitory Factor 1 (MPIF1) ELISA Kit | MPIF1 elisa kit

Human Myeloid Progenitor Inhibitory Factor 1 (MPIF1) ELISA Kit

Cat. Num. AAA453133

• Gene Names: CCL23; CKb8; MIP3; Ckb-8; MIP-3; MPIF-1; SCYA23; Ckb-8-1; hmrp-2a; CK-BETA-8
• Reactivity: Human
• Synonyms: Myeloid Progenitor Inhibitory Factor 1 (MPIF1); Human Myeloid Progenitor Inhibitory Factor 1 (MPIF1) ELISA Kit; CCL23; SCYA23; Ckb-8; MIP-3; CKb8; Chemokine(C-C-Motif)ligand 23; Small Inducible Cytokine Subfamily A(Cys-Cys)Member 23; Macrophage inflammatory protein 3; MPIF1 elisa kit

• Reactivity: Human
• Sequence Length: 137

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 15.625-1000pg/mL
• Sensitivity: 5.4pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 632794829
• NCBI GeneID: 6368
• NCBI Accession #: NP_005055.3
• NCBI GenBank Nucleotide #: NM_005064.5
• UniProt Accession #: P55773; O00174; O75950; Q52LD4; B7ZKQ3
• Molecular Weight: 15,290 Da
• NCBI Official Full Name: C-C motif chemokine 23 isoform CKbeta8-1
• NCBI Official Synonym Full Names: C-C motif chemokine ligand 23
• NCBI Official Symbol: CCL23
• NCBI Official Synonym Symbols: CKb8; MIP3; Ckb-8; MIP-3; MPIF-1; SCYA23; Ckb-8-1; hmrp-2a; CK-BETA-8
• NCBI Protein Information: C-C motif chemokine 23
• UniProt Protein Name: C-C motif chemokine 23
• UniProt Gene Name: CCL23
• UniProt Synonym Gene Names: MIP3; MPIF1; SCYA23; CKB-8; MIP-3; MPIF-1

NCBI Description

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

Uniprot Description

Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.