Human Mitogen-Activated Protein Kinase 7 (MAPK7) ELISA Kit | MAPK7 elisa kit

Human Mitogen-Activated Protein Kinase 7 (MAPK7) ELISA Kit

Cat. Num. AAA9918144

• Gene Names: Mapk7; Bmk1; Erk5; Prkm7
• Reactivity: Human
• Synonyms: Mitogen-Activated Protein Kinase 7 (MAPK7); Human Mitogen-Activated Protein Kinase 7 (MAPK7) ELISA Kit; MAPK7 elisa kit

• Reactivity: Human

• Samples: Rat Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for MAPK7 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of MAPK7 (hereafter termed "analyte") in undiluted original Rat body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 300796750
• NCBI GeneID: 114509
• NCBI Accession #: NP_001178476.1
• NCBI GenBank Nucleotide #: NM_001191547.1
• UniProt Accession #: P0C865
• Molecular Weight: 87,827 Da
• NCBI Official Full Name: mitogen-activated protein kinase 7
• NCBI Official Synonym Full Names: mitogen-activated protein kinase 7
• NCBI Official Symbol: Mapk7
• NCBI Official Synonym Symbols: Bmk1; Erk5; Prkm7
• NCBI Protein Information: mitogen-activated protein kinase 7
• UniProt Protein Name: Mitogen-activated protein kinase 7
• UniProt Gene Name: Mapk7
• UniProt Synonym Gene Names: Bmk1; Erk5; MAP kinase 7; MAPK 7; BMK-1; ERK-5

NCBI Description

binds and phosphorylates myocyte enhancer factor 2 (Mef2); may regulate Mef2 transcription activator function [RGD, Feb 2006]

Uniprot Description

Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression (). Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction ().