Human lymphotactin, Lptn/LTN ELISA Kit | Lptn/LTN elisa kit

Human lymphotactin, Lptn/LTN ELISA Kit

Cat. Num. AAA164393

• Gene Names: XCL1; LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
• Reactivity: Human
• Synonyms: lymphotactin; Lptn/LTN; Human lymphotactin; Lptn/LTN ELISA Kit; Lptn/LTN elisa kit

• Reactivity: Human
• Sequence Length: 114

• Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 5ng/L - 1000ng/L
• Sensitivity: 2.55ng/L
• Intra-Assay: CV<8%
• Inter-Assay: CV<10%
• Preparation and Storage: Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Lptn/LTN elisa kit

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Lymphotactin (also known as Lptn/LTN) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human Lptn/LTN antibody. Lptn/LTN present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human Lptn/LTN Antibody is added and binds to Lptn/LTN in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated Lptn/LTN antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human Lptn/LTN. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

• NCBI GI #: 4506853
• NCBI GeneID: 6375
• NCBI Accession #: NP_002986.1
• NCBI GenBank Nucleotide #: NM_002995.2
• UniProt Accession #: P47992; Q52MA8
• Molecular Weight: 12,517 Da
• NCBI Official Full Name: lymphotactin
• NCBI Official Synonym Full Names: X-C motif chemokine ligand 1
• NCBI Official Symbol: XCL1
• NCBI Official Synonym Symbols: LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a
• NCBI Protein Information: lymphotactin
• UniProt Protein Name: Lymphotactin
• UniProt Gene Name: XCL1
• UniProt Synonym Gene Names: LTN; SCYC1

NCBI Description

This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014]

Uniprot Description

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.