Human Laminin Alpha 5 (LAMa5) ELISA Kit | LAMa5 elisa kit

Human Laminin Alpha 5 (LAMa5) ELISA Kit

Cat. Num. AAA9308671

• Reactivity: Human
• Synonyms: Laminin Alpha 5 (LAMa5); Human Laminin Alpha 5 (LAMa5) ELISA Kit; LAMa5 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
• Assay Type: Sandwich
• Detection Range: 3.12 ng/ml - 100 ng/ml.
• Sensitivity: 1.0 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for LAMa5 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of LAMA5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 21264602
• NCBI GeneID: 3911
• NCBI Accession #: NP_005551.3
• NCBI GenBank Nucleotide #: NM_005560.4
• UniProt Accession #: O15230; Q8TDF8; Q8WZA7; Q9H1P1
• Molecular Weight: 399,737 Da
• NCBI Official Full Name: laminin subunit alpha-5
• NCBI Official Synonym Full Names: laminin, alpha 5
• NCBI Official Symbol: LAMA5
• NCBI Protein Information: laminin subunit alpha-5; laminin alpha-5 chain; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha
• UniProt Protein Name: Laminin subunit alpha-5
• Protein Family: Laminin
• UniProt Gene Name: LAMA5
• UniProt Synonym Gene Names: KIAA0533; KIAA1907
• UniProt Entry Name: LAMA5_HUMAN

NCBI Description

This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]

Uniprot Description

LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Extracellular matrix

Chromosomal Location of Human Ortholog: 20q13.2-q13.3

Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus

Molecular Function: integrin binding; structural molecule activity

Biological Process: focal adhesion formation; muscle development; extracellular matrix organization and biogenesis; regulation of embryonic development; regulation of cell migration; extracellular matrix disassembly; morphogenesis of embryonic epithelium; hair follicle development; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; integrin-mediated signaling pathway; regulation of cell adhesion; endothelial cell differentiation; cell migration; cytoskeleton organization and biogenesis; cell recognition; regulation of cell proliferation; odontogenesis of dentine-containing teeth; cell proliferation; embryonic development; ureteric bud branching; lung development