Human KIAA0174 ELISA Kit | KIAA0174 elisa kit
Human IST1 homolog, KIAA0174 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Uniprot Description
IST1: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. Belongs to the IST1 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Cell cycle regulation
Chromosomal Location of Human Ortholog: 16q22.2
Cellular Component: centrosome; cytoplasmic membrane-bound vesicle; ER-Golgi intermediate compartment; midbody; cytosol
Molecular Function: protein domain specific binding; protein binding; protein complex binding
Biological Process: release of virus from host; protein localization; establishment of protein localization; positive regulation of proteolysis; cell division; abscission; cytokinesis; viral capsid re-envelopment; positive regulation of collateral sprouting
Research Articles on KIAA0174
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Product Notes
The Human KIAA0174 ist1 (Catalog #AAA9331008) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331008 ELISA Kit recognizes Human KIAA0174. It is sometimes possible for the material contained within the vial of "KIAA0174, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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