Human IL-5 ELISA Kit | IL-5 elisa kit

IL-5 (Human) OmniKine ELISA Kit

Cat. Num. AAA9501866

• Gene Names: IL5; EDF; TRF; IL-5
• Reactivity: Human
• Synonyms: IL-5; IL-5 (Human) OmniKine ELISA Kit; Interleukin-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; IL-5 elisa kit

• Reactivity: Human
• Specificity: The OmniKine Human IL-5 ELISA is capable of recognizing both recombinant and naturally produced Human IL-5 proteins. The antigens listed below were tested at 50 ng/ml and exhibited less than 1% cross reactivity.; Murine: IL-5; The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.; Human: IL-3, IL-4, GM-CSF, SCF, TPO; Rat: IL-5
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 134

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 32-2000 pg/ml
• Sensitivity: 32-2000 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human IL-5 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-5 proteins within the range of 32-2000 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 4504671
• NCBI GeneID: 3567
• NCBI Accession #: NP_000870.1
• NCBI GenBank Nucleotide #: NM_000879.2
• UniProt Accession #: P05113; Q13840
• Molecular Weight: 15,238 Da
• NCBI Official Full Name: interleukin-5
• NCBI Official Synonym Full Names: interleukin 5
• NCBI Official Symbol: IL5
• NCBI Official Synonym Symbols: EDF; TRF; IL-5
• NCBI Protein Information: interleukin-5
• UniProt Protein Name: Interleukin-5
• UniProt Gene Name: IL5
• UniProt Synonym Gene Names: IL-5; TRF

NCBI Description

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]

Uniprot Description

IL5: Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. Belongs to the IL-5 family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular region; extracellular space; intracellular

Molecular Function: cytokine activity; growth factor activity; interleukin-5 receptor binding; protein binding; protein tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity

Biological Process: cytokine-mediated signaling pathway; immune response; inflammatory response; MAPK cascade; peptidyl-tyrosine phosphorylation; positive regulation of B cell proliferation; positive regulation of eosinophil differentiation; positive regulation of GTPase activity; positive regulation of immunoglobulin secretion; positive regulation of JAK-STAT cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of transcription factor activity; positive regulation of transcription, DNA-templated