Human IL-12/IL-23 ELISA Kit | IL-12/IL-23 elisa kit

Human IL-12/IL-23 p40 ELISA Kit

Cat. Num. AAA9135733

• Gene Names: IL12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
• Reactivity: Human
• Synonyms: IL-12/IL-23; Human IL-12/IL-23 p40 ELISA Kit; IL-12/IL-23 elisa kit

• Reactivity: Human
• Sequence Length: 328

• Assay Type: Sandwich ELISA
• Samples: Cell Culture Supernatant, Serum, Plasma (EDTA, Citrate, Heparin)
• Detection Range: 31.25-2000 pg/mL
• Sensitivity: 7 pg/mL
• Detection: Colorimetric
• Conjugate: HRP
• Preparation and Storage: Store at 4 degree C.

Typical Testing Data/Standard Curve

(Human IL-12/IL-23 p40 ELISA Kit)

Related Product Information for IL-12/IL-23 elisa kit

Product Overview: The ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of samples in cell culture supernatant, serum, plasma (EDTA, citrate, heparin).
Intended Use: This Human IL-12/IL-23 p40 ELISA kit is intended for laboratory research use only. The stop solution changes color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration of Human IL-12/IL-23 p40 in the sample, this Human IL-12/IL-23 p40 ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of optical density versus Human IL-12/IL-23 p40 concentration. The concentration of the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 24497438
• NCBI GeneID: 3593
• NCBI Accession #: NP_002178.2
• NCBI GenBank Nucleotide #: NM_002187.2
• UniProt Accession #: P29460
• Molecular Weight: 37,169 Da
• NCBI Official Full Name: interleukin-12 subunit beta
• NCBI Official Synonym Full Names: interleukin 12B
• NCBI Official Symbol: IL12B
• NCBI Official Synonym Symbols: CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
• NCBI Protein Information: interleukin-12 subunit beta
• UniProt Protein Name: Interleukin-12 subunit beta
• UniProt Gene Name: IL12B
• UniProt Synonym Gene Names: NKSF2; IL-12B; CLMF p40; NKSF2

NCBI Description

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]

Uniprot Description

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.