Human Histidine-Rich Glycoprotein ELISA Kit | Hrg elisa kit

Human Histidine-Rich Glycoprotein ELISA Kit

Cat. Num. AAA3803082

• Gene Names: Hrg; HPRG; HRG1
• Reactivity: Human
• Synonyms: Histidine-Rich Glycoprotein; Human Histidine-Rich Glycoprotein ELISA Kit; Hrg elisa kit

• Reactivity: Human
• Sequence Length: 515

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 25 mug/ml-400 mug/ml
• Sensitivity: 1 mug/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Hrg elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofHISTIDINE-RICH GLYCOPROTEINin the sample, This HISTIDINE-RICH GLYCOPROTEINELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusHISTIDINE-RICH GLYCOPROTEINconcentration. The concentration ofHISTIDINE-RICH GLYCOPROTEINin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 1049480119
• NCBI GeneID: 171016
• NCBI Accession #: NP_001316829.1
• NCBI GenBank Nucleotide #: NP_001316829.1
• UniProt Accession #: Q99PS8
• NCBI Official Full Name: similar to histidine-rich glycoprotein
• NCBI Official Synonym Full Names: histidine-rich glycoprotein
• NCBI Official Symbol: Hrg
• NCBI Official Synonym Symbols: HPRG; HRG1
• NCBI Protein Information: histidine-rich glycoprotein
• UniProt Protein Name: Histidine-rich glycoprotein
• Protein Family: Histidine-rich glycoprotein
• UniProt Gene Name: Hrg
• UniProt Synonym Gene Names: Hrg1; HPRG; HRG1

NCBI Description

plasma protein that may play a role in immune response and blood clotting [RGD, Feb 2006]

Uniprot Description

Plasma glycoprotein that binds a number of ligands such as heme, heparin, heparan sulfate, thrombospondin, plasminogen, and divalent metal ions. Inhibits rosette formation. Acts as an adapter protein and implicated in regulating many processes such as immune complex and pathogen clearance, cell adhesion, angiogenesis, coagulation and fibrinolysis. Mediates clearance of necrotic cells through enhancing the phagocytosis of necrotic cells in a heparan sulfate-dependent pathway. This process can be regulated by the presence of certain HRG ligands such as heparin and zinc ions. Binds to IgG subclasses of immunoglobins containing kappa and lambda light chains with different affinities regulating their clearance and inhibiting the formation of insoluble immune complexes. Tethers plasminogen to the cell surface. Binds T-cells and alters the cell morphology. Modulates angiogenesis by blocking the CD6-mediated antiangiongenic effect of thrombospondins, THBS1 and THBS2 ().