Human Gastrin Releasing Peptide (GRP) ELISA Kit | GRP elisa kit

Human Gastrin Releasing Peptide (GRP) ELISA Kit

Cat. Num. AAA456000

• Gene Names: GRP; BN; GRP-10; proGRP; preproGRP
• Reactivity: Human
• Synonyms: Gastrin Releasing Peptide (GRP); Human Gastrin Releasing Peptide (GRP) ELISA Kit; BN GRP10 Bombesin Neuromedin C; GRP elisa kit

• Reactivity: Human
• Sequence Length: 141

• Samples: Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
• Assay Type: Competitive inhibition
• Detection Range: 15.625-1000pg/mL
• Sensitivity: 4.64pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 60498997
• NCBI GeneID: 2922
• NCBI Accession #: NP_001012530.1
• NCBI GenBank Nucleotide #: NM_001012512.2
• UniProt Accession #: P07492; P07491; P81553; Q14454; Q53YA0; Q9BSY7
• Molecular Weight: 15,533 Da
• NCBI Official Full Name: gastrin-releasing peptide isoform 2
• NCBI Official Synonym Full Names: gastrin releasing peptide
• NCBI Official Symbol: GRP
• NCBI Official Synonym Symbols: BN; GRP-10; proGRP; preproGRP
• NCBI Protein Information: gastrin-releasing peptide
• UniProt Protein Name: Gastrin-releasing peptide
• Protein Family: Gastrin-releasing peptide
• UniProt Gene Name: GRP
• UniProt Synonym Gene Names: GRP

NCBI Description

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Uniprot Description

GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear ().