Human Filamin C Gamma (FLNC) ELISA Kit | FLNC elisa kit

Human Filamin C Gamma (FLNC) ELISA Kit

Cat. Num. AAA453195

• Gene Names: FLNC; ABPA; ABPL; FLN2; MFM5; MPD4; RCM5; CMH26; ABP-280; ABP280A
• Reactivity: Human
• Synonyms: Filamin C Gamma (FLNC); Human Filamin C Gamma (FLNC) ELISA Kit; ABP-280; ABP280A; ABPA; ABPL; FLN2; Actin Binding Protein 280; ABP-280-like protein; Actin-binding-like protein; Filamin-2; FLNC elisa kit

• Reactivity: Human
• Sequence Length: 2692

• Samples: Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.126ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 188595687
• NCBI GeneID: 2318
• NCBI Accession #: NP_001120959.1
• NCBI GenBank Nucleotide #: NM_001127487.1
• UniProt Accession #: Q14315; O95303; Q07985; Q9NS12; Q9NYE5; Q9UMR8; Q9Y503; B2ZZ88
• Molecular Weight: 287,281 Da
• NCBI Official Full Name: filamin-C isoform b
• NCBI Official Synonym Full Names: filamin C
• NCBI Official Symbol: FLNC
• NCBI Official Synonym Symbols: ABPA; ABPL; FLN2; MFM5; MPD4; RCM5; CMH26; ABP-280; ABP280A
• NCBI Protein Information: filamin-C
• UniProt Protein Name: Filamin-C
• Protein Family: Filamin
• UniProt Gene Name: FLNC
• UniProt Synonym Gene Names: ABPL; FLN2; FLN-C; FLNc

NCBI Description

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.