Human Ephrin A2 (EFNA2) ELISA Kit | EFNA2 elisa kit
Human Ephrin A2 (EFNA2) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the epha2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis
By similarity.
Subunit structure: Binds to the receptor tyrosine kinases epha2, epha3, epha4 and epha5. Interacts with epha8; activates epha8
By similarity.
Subcellular location: Cell membrane; Lipid-anchor › GPI-anchor
Potential.
Tissue specificity: Widespread expression in the embryo.
Developmental stage: Expressed in the presumptive midbrain of developing embryos from the six-somite stage. By 24 hours, expressed throughout the midbrain including the region of the presumptive tectum. At later stages, expressed in a graded fashion throughout the tectum.
Sequence similarities: Belongs to the ephrin family.Contains 1 ephrin RBD (ephrin receptor-binding) domain.
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Product Notes
The Human EFNA2 efna2 (Catalog #AAA9312502) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9312502 ELISA Kit recognizes Human EFNA2. It is sometimes possible for the material contained within the vial of "Ephrin A2 (EFNA2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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