Human E3 ubiquitin-protein ligase TRIM22 ELISA Kit | TRIM22 elisa kit
Human E3 ubiquitin-protein ligase TRIM22 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TRIM22: Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV). Acts as a transcriptional repressor of HBV core promoter. May have E3 ubiquitin-protein ligase activity. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.3.2.-; Ligase; Transcription, coactivator/corepressor; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus
Molecular Function: protein binding; protein binding, bridging; protein kinase binding; transcription corepressor activity; transcription factor activity
Biological Process: activation of NF-kappaB transcription factor; immune response; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; regulation of protein localization; regulation of transcription, DNA-dependent; response to virus
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Product Notes
The Human TRIM22 trim22 (Catalog #AAA9428477) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9428477 ELISA Kit recognizes Human TRIM22. It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase TRIM22, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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