Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Diacylglycerol kinase zeta (DGKZ) Standard Curve.)
Human Diacylglycerol Kinase zeta (DGKZ) ELISA Kit | DGKZ elisa kit
Human Diacylglycerol Kinase zeta (DGKZ) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Diacylglycerol kinase zeta (DGKZ) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Diacylglycerol kinase zeta (DGKZ) Standard Curve.)
Background: The protein encoded by DGKZ belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]
Uniprot Description
DGKZ: Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity. Belongs to the eukaryotic diacylglycerol kinase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Kinase, lipid; Lipid Metabolism - glycerolipid; EC 2.7.1.107; Lipid Metabolism - glycerophospholipid
Chromosomal Location of Human Ortholog: 11p11.2
Cellular Component: nucleoplasm; lamellipodium; cytoplasm; plasma membrane; nucleus
Molecular Function: enzyme inhibitor activity; protein C-terminus binding; lipid kinase activity; protein binding; metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity
Biological Process: G1 DNA damage checkpoint; platelet activation; cell migration; negative regulation of catalytic activity; protein kinase C activation; negative regulation of Ras protein signal transduction; negative regulation of mitotic cell cycle; lipid phosphorylation; blood coagulation; phosphorylation
Research Articles on DGKZ
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Product Notes
The Human DGKZ dgkz (Catalog #AAA9715739) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715739 ELISA Kit recognizes Human DGKZ. It is sometimes possible for the material contained within the vial of "Diacylglycerol Kinase zeta (DGKZ), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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