Human CXC-chemokine receptor 1 (CXCR1) ELISA Kit | CXCR1 elisa kit

Human CXC-chemokine receptor 1 (CXCR1) ELISA Kit

Cat. Num. AAA266284

• Gene Names: Cxcr1; Il8ra
• Reactivity: Human
• Synonyms: CXC-chemokine receptor 1 (CXCR1); Human CXC-chemokine receptor 1 (CXCR1) ELISA Kit; CXCR1 elisa kit

• Reactivity: Human
• Specificity: No cross-reaction with other factors.
• Sequence Length: 351

• Samples: Serum, plasma or cell culture supernatant and organizations in the natural and recombinant CXCR1 concentration.
• Assay Type: Sandwich
• Detection Range: 20 ng/ml-0.312 ng/ml
• Sensitivity: 0.06 ng/ml.
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for CXCR1 elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human CXCR1 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 30142679
• NCBI GeneID: 227288
• NCBI Accession #: NP_839972.1
• NCBI GenBank Nucleotide #: NM_178241.4
• Molecular Weight: 40,032 Da
• NCBI Official Full Name: C-X-C chemokine receptor type 1
• NCBI Official Synonym Full Names: chemokine (C-X-C motif) receptor 1
• NCBI Official Symbol: Cxcr1
• NCBI Official Synonym Symbols: Il8ra
• NCBI Protein Information: C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; IL-8R A; CXC chemokine receptor 1; interleukin 8 receptor, alpha; high affinity interleukin-8 receptor A
• UniProt Protein Name: C-X-C chemokine receptor type 1
• Protein Family: C-X-C chemokine receptor
• UniProt Gene Name: Cxcr1
• UniProt Synonym Gene Names: Il8ra; CXC-R1; CXCR-1; IL-8R A
• UniProt Entry Name: CXCR1_MOUSE

Uniprot Description

IL8RA: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, cytokine; Membrane protein, integral; Receptor, GPCR

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; signal transducer activity; interleukin-8 receptor activity; chemokine receptor activity; interleukin-8 binding; C-X-C chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; cell surface receptor linked signal transduction; receptor internalization; signal transduction; chemotaxis