Human Complement factor H-related protein 2 (CFHR2) ELISA Kit | CFHR2 elisa kit

Human Complement factor H-related protein 2 (CFHR2) ELISA Kit

Cat. Num. AAA167548

• Gene Names: CFHR2; FHR2; HFL3; CFHL2
• Reactivity: Human
• Synonyms: Complement factor H-related protein 2 (CFHR2); Human Complement factor H-related protein 2 (CFHR2) ELISA Kit; CFHR2 elisa kit

• Reactivity: Human
• Sequence Length: 270

• Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 2ng/ml - 600ng/ml
• Sensitivity: 1.09ng/ml
• Intra-Assay: CV<8%
• Inter-Assay: CV<10%
• Preparation and Storage: Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for CFHR2 elisa kit

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Complement Factor H-related Protein 2 (also known as CFHR2) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human CFHR2 antibody. CFHR2 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human CFHR2 Antibody is added and binds to CFHR2 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated CFHR2 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human CFHR2. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

• NCBI GI #: 5031695
• NCBI GeneID: 3080
• NCBI Accession #: NP_005657.1
• NCBI GenBank Nucleotide #: NM_005666.4
• UniProt Accession #: P36980; Q14310; Q5T9T1
• Molecular Weight: 27,897 Da
• NCBI Official Full Name: complement factor H-related protein 2 isoform 1
• NCBI Official Synonym Full Names: complement factor H related 2
• NCBI Official Symbol: CFHR2
• NCBI Official Synonym Symbols: FHR2; HFL3; CFHL2
• NCBI Protein Information: complement factor H-related protein 2
• UniProt Protein Name: Complement factor H-related protein 2
• Protein Family: Complement factor H-related protein
• UniProt Gene Name: CFHR2
• UniProt Synonym Gene Names: CFHL2; FHR2; HFL3; FHR-2

NCBI Description

This gene belongs to a family of complement factor H-related genes (CFHR), which are clustered together with complement factor H gene on chromosome 1, and are involved in regulation of complement. Mutations in CFHR genes have been associated with dense deposit disease and atypical haemolytic-uraemic syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]

Uniprot Description

Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.