Human Complement Component 1, Q Subcomponent C (C1qC) ELISA Kit | C1qC elisa kit

Human Complement Component 1, Q Subcomponent C (C1qC) ELISA Kit

Cat. Num. AAA451428

• Gene Names: C1QC; C1QG; C1Q-C
• Reactivity: Human
• Synonyms: Complement Component 1; Q Subcomponent C (C1qC); Human Complement Component 1; Q Subcomponent C (C1qC) ELISA Kit; C1QG; Complement Component 1 q subcomponent; Gamma Polypeptide; C1qC elisa kit

• Reactivity: Human
• Sequence Length: 245

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 31.25-2000pg/mL
• Sensitivity: 14.8pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 166235903
• NCBI GeneID: 714
• NCBI Accession #: NP_001107573.1
• NCBI GenBank Nucleotide #: NM_001114101.2
• UniProt Accession #: P02747; Q7Z502; Q96DL2; Q96H05
• Molecular Weight: 25,774 Da
• NCBI Official Full Name: complement C1q subcomponent subunit C isoform 1
• NCBI Official Synonym Full Names: complement C1q C chain
• NCBI Official Symbol: C1QC
• NCBI Official Synonym Symbols: C1QG; C1Q-C
• NCBI Protein Information: complement C1q subcomponent subunit C
• UniProt Protein Name: Complement C1q subcomponent subunit C
• Protein Family: Complement C1q subcomponent
• UniProt Gene Name: C1QC
• UniProt Synonym Gene Names: C1QG

NCBI Description

This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]

Uniprot Description

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.