LILRA1/LIR-6/CD85i Recombinant Protein | LILRA1 recombinant protein

LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc Tag)

Cat. Num. AAA8122092

• Gene Names: LILRA1; LIR6; CD85I; LIR-6
• Purity: >90% as determined by SDS-PAGE
• Synonyms: LILRA1/LIR-6/CD85i; LILRA1/LIR-6/CD85i Protein; Human; Recombinant (hFc Tag); Human LILRA1/LIR-6/CD85i Protein (Fc Tag); CD85I Protein; LIR-6 Protein; LIR6 Protein; leukocyte immunoglobulin like receptor A1; LILRA1 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Asn461

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: Pro 17
• Tag: C-human IgG1-Fc
• Protein Construction: A DNA sequence encoding the human LILRA1 (NP_006854.1)(Met1-Asn461) was expressed with the Fc region of human IgG1 at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 5803066
• NCBI GeneID: 11024
• NCBI Accession #: NP_006854.1
• NCBI GenBank Nucleotide #: NM_006863.3
• UniProt Accession #: O75019; O75018; Q3MJA6
• Molecular Weight: 53,275 Da
• NCBI Official Full Name: leukocyte immunoglobulin-like receptor subfamily A member 1 isoform 1
• NCBI Official Synonym Full Names: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
• NCBI Official Symbol: LILRA1
• NCBI Official Synonym Symbols: LIR6; CD85I; LIR-6
• NCBI Protein Information: leukocyte immunoglobulin-like receptor subfamily A member 1; CD85 antigen-like family member I; leukocyte immunoglobulin-like receptor 6
• UniProt Protein Name: Leukocyte immunoglobulin-like receptor subfamily A member 1
• Protein Family: Leukocyte immunoglobulin-like receptor subfamily
• UniProt Gene Name: LILRA1
• UniProt Synonym Gene Names: LIR6; LIR-6
• UniProt Entry Name: LIRA1_HUMAN

NCBI Description

This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Uniprot Description

LILRA1: May act as receptor for class I MHC antigens. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to membrane; plasma membrane

Molecular Function: transmembrane receptor activity; antigen binding

Biological Process: regulation of immune response; cell surface receptor linked signal transduction; immune system process; defense response