Human Complement 1q (C1q) ELISA Kit | C1q elisa kit

Human Complement 1q (C1q) ELISA Kit

Cat. Num. AAA264772

• Gene Names: C1QTNF5; CTRP5
• Reactivity: Human
• Synonyms: Complement 1q (C1q); Human Complement 1q (C1q) ELISA Kit; C1q elisa kit

• Reactivity: Human
• Sequence Length: 243

• Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant Complement 1q (C1q) concentration
• Assay Type: Sandwich
• Detection Range: 500 ng/ml-7.8 ng/ml
• Sensitivity: 0.7ng/ml.
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for C1q elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human C1q monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 510025462
• NCBI GeneID: 114902
• NCBI Accession #: NP_001265360.1
• NCBI GenBank Nucleotide #: NM_001278431.1
• Molecular Weight: 25,298 Da
• NCBI Official Full Name: complement C1q tumor necrosis factor-related protein 5
• NCBI Official Synonym Full Names: C1q and tumor necrosis factor related protein 5
• NCBI Official Symbol: C1QTNF5
• NCBI Official Synonym Symbols: CTRP5
• NCBI Protein Information: complement C1q tumor necrosis factor-related protein 5; myonectin; C1q TNF-alpha-related protein 5
• UniProt Protein Name: Complement C1q tumor necrosis factor-related protein 5
• UniProt Gene Name: C1QTNF5
• UniProt Synonym Gene Names: CTRP5; UNQ303/PRO344
• UniProt Entry Name: C1QT5_HUMAN

NCBI Description

This gene encodes a member of a family of proteins that function as components of basement membranes and may play a role in cell adhesion. Mutations in this gene have been associated with late-onset retinal degeneration. The protein may be encoded by either a bicistronic transcript including sequence from the upstream membrane frizzled-related protein gene (MFRP), or by a monocistronic transcript expressed from an internal promoter. [provided by RefSeq, Jun 2013]

Uniprot Description

C1QTNF5: Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD). LORD is an autosomal dominant disorder characterized by onset in the fifth to sixth decade with night blindness and punctate yellow-white deposits in the retinal fundus, progressing to severe central and peripheral degeneration, with choroidal neovascularization and chorioretinal atrophy.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: collagen

Disease: Late-onset Retinal Degeneration