Typical Testing Data/Standard Curve (for reference only)

Human Chemokine C-C-Motif Ligand 4 (CCL4) ELISA Kit | CCL4 elisa kit

Human Chemokine C-C-Motif Ligand 4 (CCL4) ELISA Kit

Gene Names

CCL4; ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta

Reactivity

Human

Synonyms

Chemokine C-C-Motif Ligand 4 (CCL4); Human Chemokine C-C-Motif Ligand 4 (CCL4) ELISA Kit; CCL4 elisa kit

Ordering
Cat. Num. AAA3802573 For Research Use Only!

Reactivity

Human

Sequence Length

Samples

Serum, plasma, cell culture supernate and other biological fluids

Assay Type

Sandwich

Detection Range

4ng/ml-64ng/ml

Sensitivity

0.1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for CCL4 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofCCL4in the sample, This CCL4ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusCCL4concentration. The concentration ofCCL4in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #

4506845

NCBI GeneID

6351

NCBI Accession #

NCBI GenBank Nucleotide #

NP_002975.1

UniProt Accession #

P13236

NCBI Official Full Name

C-C motif chemokine 4

NCBI Official Synonym Full Names

C-C motif chemokine ligand 4

NCBI Official Symbol

CCL4

NCBI Official Synonym Symbols

ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta

NCBI Protein Information

C-C motif chemokine 4

UniProt Protein Name

C-C motif chemokine 4

Protein Family

C-C motif chemokine

UniProt Gene Name

CCL4

UniProt Synonym Gene Names

LAG1; MIP1B; SCYA4; LAG-1; MIP-1-beta; ACT-2

UniProt Entry Name

CCL4_HUMAN

NCBI Description

The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012]

Uniprot Description

CCL4: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space; extracellular region

Molecular Function: identical protein binding; protein binding; CCR1 chemokine receptor binding; chemokine activity; cytokine activity; CCR5 chemokine receptor binding

Biological Process: cell-cell signaling; response to toxin; response to virus; establishment and/or maintenance of cell polarity; positive regulation of calcium-mediated signaling; immune response; positive regulation of calcium ion transport; inflammatory response; cell motility; signal transduction; cell adhesion

Research Articles on CCL4

1. study showed contribution of CCL3 and CCL4 in multiple sclerosis pathogenesis and suggested them as markers of severity of disease; investigation of chemokines responsible for attraction of pathogenic T lymphocyte and macrophage in to the central nerves system(CNS) is crucial for therapeutic targets in MS

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Product Notes

The Human CCL4 ccl4 (Catalog #AAA3802573) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3802573 ELISA Kit recognizes Human CCL4. It is sometimes possible for the material contained within the vial of "Chemokine C-C-Motif Ligand 4 (CCL4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Human Chemokine C-C-Motif Ligand 4 (CCL4) ELISA Kit | CCL4 elisa kit