Human CD28 ELISA Kit | CD28 elisa kit

QuickDetect CD28 (Human) ELISA Kit

Cat. Num. AAA846760

• Reactivity: Human
• Synonyms: CD28; QuickDetect CD28 (Human) ELISA Kit; CD28 elisa kit

• Reactivity: Human
• Sequence Length: 63

• Samples: Serum, plasma and cell culture and other biological fluid
• Assay Type: Quantitative Sandwich
• Detection Range: 6.25 - 400 ng/ml
• Preparation and Storage: Store at 4 degree C for 6 months.

Typical Standard Curve/Testing Data

Related Product Information for CD28 elisa kit

Background/Introduction: CD28 involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. QuickDetectTM CD28 ELISA kit is a sandwich ELISA assay for measuring the quantity of human CD28 in serum, plasma and cell culture and other biological fluid. The entire process can be performed within 90 minutes with only a single incubation and a wash step respectively, resulting in fewer handling steps, fewer errors and more consistent results.

NCBI and Uniprot Product Information

• NCBI GI #: 192485
• NCBI GeneID: 12487
• Molecular Weight: 25,243 Da
• NCBI Official Full Name: CD28, partial
• NCBI Official Synonym Full Names: CD28 antigen
• NCBI Official Symbol: Cd28
• NCBI Protein Information: T-cell-specific surface glycoprotein CD28
• UniProt Protein Name: T-cell-specific surface glycoprotein CD28
• Protein Family: T-cell-specific surface glycoprotein
• UniProt Gene Name: Cd28

Uniprot Description

CD28: a type I plasma membrane protein Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Binds to B7-1 and -2. Expressed in T cells and plasma cells, but not in less mature B cells. Six splice-variant isoforms have been described.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1 C2|1 30.52 cM

Cellular Component: cell surface; external side of plasma membrane; immunological synapse; lipid raft; plasma membrane

Molecular Function: protease binding; protein homodimerization activity; protein kinase binding; SH3/SH2 adaptor activity

Biological Process: negative thymic T cell selection; positive regulation of alpha-beta T cell proliferation; positive regulation of inflammatory response to antigenic stimulus; positive regulation of interleukin-10 production; positive regulation of interleukin-2 biosynthetic process; positive regulation of interleukin-4 production; positive regulation of isotype switching to IgG isotypes; positive regulation of mitosis; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of T cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of regulatory T cell differentiation; regulatory T cell differentiation; T cell activation; T cell costimulation; T cell receptor signaling pathway