Human Astrotactin-2 (ASTN2) ELISA Kit | ASTN2 elisa kit

Human Astrotactin-2 (ASTN2) ELISA Kit

Cat. Num. AAA2800228

• Gene Names: ASTN2; bA67K19.1
• Reactivity: Human
• Synonyms: Astrotactin-2 (ASTN2); Human Astrotactin-2 (ASTN2) ELISA Kit; RP11-45A16.2; KIAA0634; bA67K19.1; bA264C15.1 (astrotactin2); ASTN2 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human ASTN2. No significant cross-reactivity or interference between Human ASTN2 and analogues was observed.
• Sequence Length: 1288

• Assay Type: Quantitive Sandwich
• Samples: Serum, Plasma, Other Biological Fluids
• Detection Wavelength: 450 nm
• Intra-assay Precision (Precision within an assay): Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
• Inter-assay Precision (Precision between assays): Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
• CV (%): = SD/meanX100
• Intra-Assay: CV
• Inter-Assay: CV
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for ASTN2 elisa kit

This assay employs a two-site sandwich ELISA to quantitate ASTN2 in samples. An antibody specific for ASTN2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ASTN2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ASTN2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ASTN2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 46488915
• NCBI GeneID: 23245
• NCBI Accession #: NP_054729.3
• NCBI GenBank Nucleotide #: NM_014010.4
• UniProt Accession #: O75129; Q52LQ2; Q5JVX8; Q5JVX9; Q5JVY1; Q5VXG8; Q5VZX6; Q8N6P8; Q8WV47; Q96FL4; A2A2T7; A2A2T9
• Molecular Weight: 44,561 Da
• NCBI Official Full Name: astrotactin-2 isoform a
• NCBI Official Synonym Full Names: astrotactin 2
• NCBI Official Symbol: ASTN2
• NCBI Official Synonym Symbols: bA67K19.1
• NCBI Protein Information: astrotactin-2
• UniProt Protein Name: Astrotactin-2
• Protein Family: Astrotactin
• UniProt Gene Name: ASTN2
• UniProt Synonym Gene Names: KIAA0634

NCBI Description

This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]

Uniprot Description

Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref. 6).