Human 4-1BB-R ELISA Kit | 4-1BB-R elisa kit

4-1BB-R (Human) OmniKine ELISA Kit

Cat. Num. AAA9501827

• Gene Names: TNFRSF9; ILA; 4-1BB; CD137; CDw137
• Reactivity: Human
• Synonyms: 4-1BB-R; 4-1BB-R (Human) OmniKine ELISA Kit; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor T-cell; antigen 4-1BB homolog; T-cell antigen ILA; CD137 antigen; CDw137; ILA; 4-1BB; MGC2172; 4-1BBR; TNFRSF9; 4-1BB-R elisa kit

• Reactivity: Human
• Specificity: The OmniKine Human 4-1BBR ELISA is capable of recognizing both recombinant and naturally produced Human 4-1BBR proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.; Human: 4-1BBL, AITRL, BAFF, BAFF Receptor, BCMA, CD40 Ligand/TRAP, Fas Receptor, LIGHT, OPG, sOX40L, sRANK (Receptor), sRANKL, TACI, TL-1A, TNF-alpha, TNF-beta, sTNF-Receptor Type I, sTNF-Receptor Type II, sTRAIL/Apo2L, sTRAIL Receptor-1, sTRAIL Receptor-2, TWEAK, TWEAK Receptor
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 255

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 16-2000 pg/ml
• Sensitivity: 16-2000 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human 4-1BB-R ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human 4-1BB-R proteins within the range of 16-2000 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 5730095
• NCBI GeneID: 3604
• NCBI Accession #: NP_001552.2
• NCBI GenBank Nucleotide #: NM_001561.5
• UniProt Accession #: Q07011
• Molecular Weight: 27,899 Da
• NCBI Official Full Name: tumor necrosis factor receptor superfamily member 9
• NCBI Official Synonym Full Names: TNF receptor superfamily member 9
• NCBI Official Symbol: TNFRSF9
• NCBI Official Synonym Symbols: ILA; 4-1BB; CD137; CDw137
• NCBI Protein Information: tumor necrosis factor receptor superfamily member 9
• UniProt Protein Name: Tumor necrosis factor receptor superfamily member 9
• UniProt Gene Name: TNFRSF9
• UniProt Synonym Gene Names: CD137; ILA

NCBI Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

Uniprot Description

TNFRSF9: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36.23

Cellular Component: external side of plasma membrane; extracellular space; integral component of plasma membrane; plasma membrane

Molecular Function: cytokine binding; receptor activity; tumor necrosis factor-activated receptor activity

Biological Process: apoptosis; immune response; inflammatory response; multicellular organism development; negative regulation of cell proliferation; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway