Human IL-17BR CLIA Kit | IL-17BR clia kit
IL-17BR (Human) LumiAb ELISA Kit
The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: IL-17R/Fc, IL-17RC, IL-17RD
Murine: IL-17BR/Fc, IL-17RC, IL-17RD
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
Uniprot Description
IL17RB: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: interleukin-17 receptor activity
Biological Process: defense response
Research Articles on IL-17BR
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Product Notes
The Human IL-17BR il17rb (Catalog #AAA9510892) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9510892 CLIA Kit recognizes Human IL-17BR. It is sometimes possible for the material contained within the vial of "IL-17BR, CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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