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RUBCNL blocking peptide

RUBCNL Peptide - middle region

Gene Names
HAUS1; HEIC; CCDC5; HEI-C; HsT1461
Reactivity
Human
Applications
Western Blot
Synonyms
RUBCNL; RUBCNL Peptide - middle region; RUBCNL blocking peptide
Ordering
For Research Use Only!
Reactivity
Human
Form/Format
Lyophilized powder
Sequence
SKEVSGLLGSDQPDSEMTFDTNIKQESGSSTSSYSGYEGCAVLQVSPVTE
Sequence Length
635
Applicable Applications for RUBCNL blocking peptide
Western Blot (WB)
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Related Product Information for RUBCNL blocking peptide
This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients.
Product Categories/Family for RUBCNL blocking peptide

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70kDa
NCBI Official Full Name
HAUS augmin-like complex subunit 1
NCBI Official Synonym Full Names
HAUS augmin like complex subunit 1
NCBI Official Symbol
HAUS1
NCBI Official Synonym Symbols
HEIC; CCDC5; HEI-C; HsT1461
NCBI Protein Information
HAUS augmin-like complex subunit 1
UniProt Protein Name
HAUS augmin-like complex subunit 1
UniProt Gene Name
HAUS1
UniProt Synonym Gene Names
CCDC5; HEIC; HEI-C
UniProt Entry Name
HAUS1_HUMAN

NCBI Description

HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]

Uniprot Description

CCDC5: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS1 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: spindle pole; centrosome; microtubule; cytoplasm

Molecular Function: protein binding

Biological Process: mitosis; cell division; centrosome organization and biogenesis; spindle assembly

Research Articles on RUBCNL

Similar Products

Product Notes

The RUBCNL haus1 (Catalog #AAA3240588) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The RUBCNL Peptide - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RUBCNL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the RUBCNL haus1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SKEVSGLLGS DQPDSEMTFD TNIKQESGSS TSSYSGYEGC AVLQVSPVTE. It is sometimes possible for the material contained within the vial of "RUBCNL, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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