RNF35 / TRIM40 Blocking Peptide | TRIM40 blocking peptide
RNF35 / TRIM40 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the tripartite motif (TRIM) protein family. The encoded protein may play a role as a negative regulator against inflammation and carcinogenesis in the gastrointestinal tract. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]
Uniprot Description
TRIM40: May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 6p22.1
Cellular Component: IkappaB kinase complex
Molecular Function: protein binding
Biological Process: inhibition of NF-kappaB transcription factor; negative regulation of protein catabolic process; protein neddylation
Research Articles on TRIM40
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Product Notes
The TRIM40 trim40 (Catalog #AAA425172) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The RNF35 / TRIM40 Immunizing Peptide reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-GVSELLLQ PPQKL. It is sometimes possible for the material contained within the vial of "RNF35 / TRIM40, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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